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The inclusion criteria included original experimental studies (e.g., in vitro cell culture, animal models, and human studies)

Nat Reviews Immunol 2016

Romoli JCZ, Silva MV, Pante GC, Hoeltgebaum D, Castro JC, Oliveira da Rocha GH, Capoci IRG, Nerilo SB, Mossini SAG, Micotti da Gloria E, Svidzinski TIE, Graton Mikcha JM, Machinski MJ (2022) Anti-mycotoxigenic and antifungal activity of ginger, turmeric, thyme and rosemary essential oils in deoxynivalenol (DON) and zearalenone (ZEA) producing Fusarium graminearum

Turnover of cholesterol and 24(S)-hydroxycholesterol in rat brain as measured with 18O2 techniques in vivo and in vitro

It also supports regeneration of vitamin C, helping protect cells from oxidative stress

These suggests that the neuroprotective effects of berberine may be related to an excitatory mechanism that promotes cell survival and antioxidant-related signaling pathways