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Succinyl-CoA plays an important role in the production of energy from lipids and proteins and is also required for the synthesis of hemoglobin, the oxygen-carrying pigment in red blood cells (3)

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Their anti-tumor activity depends on Fc-dependent immune effector mechanisms and immunomodulatory effects that eliminate CD38 regulatory T cells and restore T-cell- and NK-cell-mediated antitumor immune responses [56]