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Regarding gender, some data have shown a differentiation between the immune response based on estradiol levels

10.1111/j.1365-2672.2009.04350.x 52

6 Applications of surface modifications on nanoparticle toxicity Surface altering techniques have been employed extensively to reduce the toxicity of nanoparticles since the translation of nanomedicine from bench to bedside has encountered many toxicity-related problems

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While designed for research purposes, their potential in sleep and recovery science continues to grow, paving the way for future advancements