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Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

Mitochondrial pyruvate carrier regulates autophagy, inflammation and neurodegeneration in experimental models of Parkinsons disease

However, oxidative stress has been linked to many diseases in older individuals, and it might be a good attempt to intervene in chronic diseases from the perspective of modulating oxidative stress