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The resulting GSH or homoglutathione (-L-glutamyl-L-cysteinyl--alanine) conjugates were usually much less toxic and more water-soluble than the original xenobiotics (Brown and Neighbors, 1) (Bartling et al., 2002

Finally, we outline future research directions, emphasizing the need for large-scale, multicenter randomized controlled trials with standardized outcomes to establish more robust evidence base and support broader international clinical adoption

(3) Maintaining Sleep Hygiene: Keep relatively fixed bedtimes and wake-up times, even on weekends

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