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GBMs were classified as classical ( n =17), mesenchymal ( n =12), or proneural ( n =6) transcriptomic subtypes

Using a synthetic mononucleosome substrate, the ability of RSC to promote nucleosome sliding can be monitored 29

JC70, Santa Cruz Biotechnology, United States) diluted in PBS containing 5% normal goat serum (NGS) and 0.02% Triton X-100

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This process constructs a malignant positive feedback loop: released NETs act as thrombotic scaffolds to further capture circulating platelets and induce their activation, promoting further P-Exos release, and ultimately leading to widespread occlusion of pulmonary microvessels

In many cases, gallstones can be managed without the need for surgery