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A notable example is the placebo-controlled trial by Bhasin et al., which demonstrated dose-dependent anabolic effects of supraphysiological testosterone enanthate administered for 10 weeks in healthy men, providing valuable mechanistic insight under rigorously controlled conditions but without addressing long-term safety outcomes ( Finally, most published studies focus predominantly on young men attending gyms, which limits the generalisability of findings to other populations, including women, adolescents, and individuals with differing health profiles or patterns of substance use

Anti-ferroptotic roles of p53 A recent study demonstrated that p53 inhibited ferroptosis by regulating the localization and activity but not the expression of dipeptidyl peptidase-4 (DPP4) in a transcription-independent manner (Fig

(PubMed) Antico A, Tampoia M, Tozzoli R, Bizzaro N

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