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These important immunosuppressive changes were associated with increased synthesis of the immunoregulatory cytokine transforming growth factor- by colonic epithelial cells in Cl-2TG mice compared with WT littermates (Figure 2)

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Research involving these pathways remains ongoing, particularly within broader investigations involving cellular-response mechanisms, oxidative-stress regulation, and tissue-maintenance research

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Region-specific remodeling of the enteric nervous system and enteroendocrine cells in the colon of spinal cord injury patients