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Benign regulation of the gut microbiota: The possible mechanism through which the beneficial effects of manual acupuncture on cognitive ability and intestinal mucosal barrier function occur in APP/PS1 mice

2.3.2 Determination of Apixaban Protein Binding An additional 5-mL blood sample for the assessment of apixaban protein binding was collected 3 h after apixaban administration into a tube containing no anticoagulant and centrifuged (15 min at 1000 g ) to obtain serum

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