(1) reported that UA does not extend the nematode lifespan through alterations in bacterial counts, metabolism, or food intake
10.1038/nmeth.1212 74 HagiwaraM.MaegawaK.-i.SuzukiM.UshiodaR.ArakiK.MatsumotoY.et al (2011)
These SNPs may affect the structural and functional integrity of the ERCC2 protein, ultimately diminishing its effectiveness in repairing DNA damage (Rouissi et al., 2011)

Johns of God Hospital Vienna, Department of Neurology, Vienna, Austria, 8 Austrian Federal Ministry of Social Affairs, Vienna, Austria, 9 Institute of Clinical Epidemiology, Public Health, Health Economics, Medical Statistics and Informatics, Medical University of Innsbruck, Innsbruck, Austria, 10 Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom, 11 Medical Faculty, Sigmund Freud University Vienna, Vienna, Austria, 12 Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universitt Erlangen-Nrnberg and Universittsklinikum Erlangen, Erlangen, Germany, 13 Deutsches Zentrum Immuntherapie, Friedrich-Alexander-Universitt Erlangen-Nrnberg and Universittsklinikum Erlangen, Erlangen, Germany, 14 Austrian Stroke Society, Vienna, Austria Background and Aims: Bone fractures are a feared post-stroke complication that increase disability and mortality

This overview should give you some interesting reading materials to work with, as well as a look at further research potential
Nanobiotechnol 20, 12