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Sporadic Alzheimer disease fibroblasts display an oxidative stress pehnotype

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Moreover, structural superposition between GSH-bound OsDHAR and glutathione disulphide (GSSG)-bound hGSTO1-1 showed dramatic helix (5, 6 and 9) movement in the C-terminal domain region of OsDHAR, which likely allows bound GSH molecules in the G- and H-sites to be sufficient close for GSSG formation (Supplemental Fig

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[DOI] [PubMed] [Google Scholar] 82.Karl J.P., Meydani M., Barnett J.B., Vanegas S.M., Barger K., Fu X., Goldin B., Kane A., Rasmussen H., Vangay P., et al

Plasma targeted metabolomics analysis for amino acids and acylcarnitines in patients with prediabetes, type 2 diabetes mellitus, and diabetic vascular complications