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However, like previous studies, researchers attributed the cytotoxicity of elesclomol to the excessive production of ROS and could not explain why the cell death induced by elesclomol was closely related to mitochondrial respiration and why the sensitivity of cells with active mitochondrial respiration to elesclomol was nearly 1000 times higher than that of cells with active glycolysis

MiR-155 inhibitor-laden exosomes reverse resistance to cisplatin in a 3D tumor spheroid and xenograft model of oral cancer

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Eur J Pharmacol 137:127129, 1987 Szabo S, Usadel KH: Cytoprotection-organoprotection by somatostatin: Gastric and hepatic lesions

By contrast, ATF7 contributes to innate immune memory by modulating STAT1/NF-B-dependent inflammatory networks (such as CXCL9/10), thus enhancing macrophage-mediated responses against bacteria and fungi (119)