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[9] These proteins are members of the family of ATP-binding cassette transporters and can catalyse the ATP-dependent transport of a huge variety of hydrophobic anions, [10] and thus act to remove phase II products to the extracellular medium, where they may be further metabolised or excreted

[DOI] [PMC free article] [PubMed] [Google Scholar] 167.Mannervik B

The FDA approved JELYMTO in 2020, and the FDA approved indication and usage for JELMYTO is as an alkylating drug indicated for the treatment of adult patients with low-grade Upper Tract Urothelial Cancer (LG-UTUS)

Additionally, metformin has been shown to improve sputum culture conversion and lower the relapse rate of patients with TB-DM [122]

Frontiers in Pharmacology, 12, 627533.

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