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In RPECs, GPX4 inhibitors such as 1s and 3R-RSL3 (RSL3) increase lysosome-associated membrane protein 2 (LAMP2) levels, leading to ferroptosis

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Clinical relevance and novel insights from HDL-C-based stratification in HS Through direct comparison with healthy controls, this study observed a significant reduction in HDL-C levels in patients with HS, providing additional support for the emerging concept of HDL-Ccentered metabolic dysregulation in this disease

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