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Agonistic antibodies reveal the function of GPR56 in human glioma U87-MG cells

However, the precise mechanism by which NMT1 integrates into the dynamic environment of the translating ribosome, and how its co-translational activity is coordinated with that of both human MetAPs and other ribosome-associated enzymes remain unclear

To investigate the role of GSS in male reproduction, we constructed Gss Flox/Flox mice by inserting two LoxP site to the left and right of exon 3 (Fig

aureus is characterized by a lipid peroxidation mechanism where AA is oxidized into reactive electrophiles, which elicit toxicity by modifying the macromolecules of S

Preclinical acute toxicity is low, with reported rodent LD50 values well above any human-equivalent research dose

The Mg 2+ -bound enzyme is catalytically active, while a low Mg 2+ state may permit small molecule inhibition at the allosteric site (Extended Data Fig