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This means the body gets used to the drug and needs it to work normally

10.1039/d3fo05222b 87 MossJ

Biomaterials 31:15021508

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When medications for weight management are used to augment lifestyle intervention, they offer a rational pathway for sustained weight loss because they result in more weight loss than can be achieved with lifestyle intervention alone

"But more systematic studies of using astaxanthin in humans are necessary to confirm the advantage of using it over a prolonged period." Astaxanthin benefits for skin Although algae astaxanthin extract slowed skin cancer cell growth, it's unclear if it works on humans