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This binding activates various oxidative stress and inflammatory signaling pathways, including TGF- and NF-B (207)

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Given that MBP expressing in OLs can be detected initially at P3 in the corpus callosum at P3 following myelinated axons seen in P10 8 , rat pups (n = 6) at P3 received the daily oral administration of crude HEM (0.1 and 1.0 mg/kg) for 7 days