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Notably, current strategies targeting lipids are not brain-specific and affect peripheral lipid biosynthesis, which is associated with increased triglyceride levels and side effects such as liver steatosis [219]

This study found that the percentage of subjects in three age groups (26 to 49y, 50 to 64y, and 65y and older) with deficient blood levels of vitamin B12 was similar across all age groups but that symptoms of B12 deficiency were not as apparent in younger adults

If you have symptoms and are concerned, please speak to your GP and request a check of your B12

[17] demonstrated that significant changes occurred in human white adipose tissue following circadian disruption due to sleep deprivation

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Notably, no tested anti- Wolbachia drug activated autophagy flux in either mammalian cell line, highlighting their restricted role in insect cells and nematodes (Supplementary Figures S1C,D)