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Possible signs that deserve a closer look include: Persistent fatigue despite adequate sleep Reduced stamina or shortness of breath with ordinary activity Brain fog or difficulty concentrating Hair shedding or brittle nails Restless legs Headaches, dizziness or feeling faint Heart palpitations Muscle weakness, cramps or reduced exercise tolerance Tingling, numbness or balance changes Iron or B12 that remains low despite supplementation These symptoms do not confirm a deficiency

Overall, the safety data for sildenafil 20 mg TID and for the higher sildenafil 80 mg TID dose were consistent with the established safety profile of sildenafil in previous adult PAH studies [see Adverse Reactions (6.1)]

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I am calling my doctor tomorrow to get this looked at