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10.1016/j.ejphar.2020.173258 21 CinatlJ.MorgensternB.BauerG.ChandraP.RabenauH.DoerrH

In STZ-induced diabetic rats, RBX effectively attenuates myocardial hypertrophy and dysfunction by suppressing PKC-2 activation, reducing NOX-mediated oxidative stress, and normalizing cardiac structure and function, with superior cardioprotection compared to NAC [173]

Low levels of glutathione are connected to severe ailments like cardiovascular issues and diabetes

The authors would also like to acknowledge BioRender for providing a platform to design graphical images

This presentation may simulate that of familial hypercholesterolemia, although tendon xanthomas have been reported to be more severe in sitosterolemia than in heterozygous familial hypercholesterolemia