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Host recognition of bacterial muramyl dipeptide mediated through NOD2

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Half maximal inhibitory concentration (IC 50 ) values were calculated using a four parameter non-linear regression curve with Graph Pad Prism v8 (GraphPad, La Jolla, CA, USA)

TrappoliereMCaligiuriASchmidMBertolaniCFailliPVizzuttiFet al

In the test system with hamster S9-mix, NMA, NDMA, and NDELA might all be considered equipotent, but with the relatively higher uncertainty (BMD 100 CI ratio: 15.4) and variability of the NMA data, a final conclusion could not be drawn

Nazem, M