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There was neither change in gcs-1 mRNA levels (Figure 3c), nor gcs-1GFP expression (Supplementary Figure S3a)

Brain Struct Funct 226:24892495

Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimers disease pathogenesis

Zileuton, an anti-inflammatory compound, inhibits LOX5 and decreases -secretase, A, and tau after three months of treatment in a 3xTg mouse AD model (Di Meco et al., 2014), demonstrating its broad prospects for clinical use

Sex differences have also been reported: women experience a higher rate of L-DOPA-induced dyskinesia (LID), anxiety and dystonia (San Luciano et al., 2017

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