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Cells 2022;11:4127

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Excess ROS acts as a second messenger and regulates the function of important proteins, including Kelch-like ECH-associated protein 1 (Keap1), protein kinase C (PKC), and IB kinase by interacting with the cysteine residues (known as redox sensors) and causes their oxidation [10,25]

10.1016/j.bioorg.2019.103031 Bioorg Chem

With low levels, you have a risk of building additional oxidative damage, which can contribute to wrinkles and poor skin elasticity