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This feature has been observed for all amphipathic helices so far reported

In gastric cancer, ROS have been found to form a self-amplifying positive feedback loop with the p38 signaling pathway, continuously driving cancer cell metastasis [111]

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doi: 10.1016/j.jdiacomp.2020.107805 111 HobsonPLewisANairHWongSKumwendaM

Figure 8 3.5 Chronic fatigue syndrome (CFS) A growing body of clinical evidence shows that the gut microbiota plays a critical role in CFS, with consistently observed reductions in butyrate-producing bacteria and enrichment of Enterobacteriaceae , together with frequent depletion of anti-inflammatory taxa such as Faecalibacterium (Knig et al., 2021