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The end products of lipid peroxidation, such as malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE), are themselves reactive and can further propagate oxidative damage [33]

Metabolic response of humans to ingestion of nicotinic acid and nicotinamide

This raises questions regarding the actual cytosolic NADP redox state and how variable it might be under different conditions or in different organisms

Further research is needed to confirm these results

10.1016/j.ejphar.2016.11.037 29 JohansenT.LamarkT

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