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Figure 5: Changes in tissue weight in lean mice and obese mice across the three different experimental treatment groups

Liposomal formulations are lightweight and can be engineered to be non-migrating, making them safe for the eye area

The compound's development represents years of medicinal chemistry optimization, resulting in a 10-fold improvement in potency over parent compounds while maintaining excellent safety margins in preclinical studies

Most lack formal human clinical trials

FEBS J (2018) 285(10):175166