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[19] Badaro R, Barbosa JD, de Araujo Neto CA, Machado BA, Soares MB, de Senna V, et al

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During inflammatory processes, triglycerides undergo hydrolysis, forming free fatty acids (FFA) (Zhu et al., 2022), which are toxic to hepatocytes and induce apoptosis through both extrinsic and intrinsic pathways ( (2) Toxic Lipid Metabolites: The metabolism of lipids produces toxic metabolites such as malondialdehyde (MDA), 4-hydroxynonenal (4-HNE), and malondialdehyde-acetaldehyde adducts (MAA), which further damage mitochondria and promote free radical production (Schaffert, 2009)

The content of GSH and nicotinamide adenine dinucleotide phosphate (NADPH) directly affects the GPX4 activity [22]

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The rich content of pyroglutamic acid in S