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at China Pharmaceutical University and Nanjing First Hospital: oral Dihexa restored spatial learning and memory in the APP/PS1 transgenic mouse model of Alzheimers disease via the PI3K/AKT signaling pathway, reduced neuroinflammation, and preserved hippocampal synaptophysin expression (Sun et al., Brain Sciences 2021)

Overexpression of p21 alone may also be sufficient to inhibit ferroptosis via interaction with cyclin dependent kinases (CDKs) in some contexts (Venkatesh et al, 2020b)

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[PubMed: 16675541] 31

Glutathione functions by inhibiting the activity of the Tyrosinase Enzyme which in turn slows down the production of Melanin responsible for the darkening of the skin