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The same HGF plasmid (VM-202) was also evaluated in ALS patients in order to define its tolerability and safety profile (NCT02039401)

HuntKAZhernakovaATurnerGHeapGARFrankeLBruinenbergMet al

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Through upregulating TP53 activity, GNA lowered the expression levels of GPX4 and SLC7A11, leading to dysregulation of cellular lipid peroxides, and eventually ferroptosis in transforming growth factor-1 (TGF-1)-induced EMT melanoma models (Wang et al., 2020)

WADA status is not a safety endorsement

It is an advisory committee meeting to discuss whether certain substances should be considered for a compounding list, and such committees issue non-binding recommendations [10]