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Yongzhong Zhao declares that he has no conflict of interest

R.RibeiroV

Furthermore, the aging process of phosphorylated AChE drastically reduces the therapeutic window for oxime reactivation, especially with certain dimethyl OPs where aging can occur within minutes

1 H NMR (400 MHz, CDCl 3 ) 8.94 (t, J = 5.3 Hz, 2H, NH 2), 7.887.62 (m, 30H, ArH 30), 3.843.67 (m, 8H, H 2 -1 2 and H 2 -6 2), 3.07 (dd, J = 11.7, 5.8 Hz, 4H, H 2 -2 2), 1.871.76 (m, 4H, H 2 -4 2), 1.711.49 (m, 8H, H 2 -3 2 and H 2 -5 2)