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For example, if you added 4 mL instead of 3 mL to a 30 mg vial, your new concentration is 30mg / 4mL = 7.5 mg/mL.

Nat Rev Microbiol 21 , 555572 (2023)

As stated earlier, NAPQI is a reactive electrophile which is an alkylating agent of the thiol groups (Rocha et al ., 2005

A vitamin B12 deficiency will likely result in a higher homocysteine level in the blood

Even if the exact conversion mechanism has not been characterised yet, a limited conversion capacity in Western populations (about 25 %) has been highlighted, as opposed to the greater competence of Asian populations (50 %), estimated through urinary equol excretion (Reference Setchell, Brown and Lydeking-Olsen17)

10.1016/j.ijbiomac.2021.12.042 52 KangY.KangX.YangH.LiuH.YangX.LiuQ.et al (2022)