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Additionally, Cai et al

Injections have better bioavailability than oral supplements as they bypass the digestive system completely, providing a direct supply of B12 into the bloodstream to fuel your body

Overexpression of NNMT has been linked to obesity, insulin resistance, and impaired NAD metabolism

[4] Based on animal research, it is thought that the increased methylmalonyl-CoA hydrolyzes to form methylmalonate (methylmalonic acid), a neurotoxic dicarboxylic acid, causing neurological deterioration

All procedures were carried out in strict accordance with the code of ethics

This means you need proportionally higher doses via nasal spray to achieve similar systemic peptide levels