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Cells were analysed by flow cytometry using a BD LSR II instrument

Estrogenic activity of 7-hydroxymatairesinol potassium acetate (HMR/lignan) from Norway spruce ( Picea abies ) knots and of its active metabolite enterolactone in MCF-7 cells

On one hand, P

doi: 10.1016/j.pharmthera.2013.09.006

Neonates are especially vulnerable due to renal immaturity, altered volume of distribution, and incomplete blood-labyrinth barrier development, which together increase both drug accumulation and cochlear susceptibility