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10.1016/j.cyto.2023.156144 17 DemirovicD.RattanS

Nccih.nih.gov

Experimental studies have demonstrated delayed RGC death in animal glaucoma models

However, lipoxygenase primarily contributes to cysteine starvation-induced ferroptosis rather than GPX4 deficiency-induced ferroptosis

Notably, oncogenes, such as KRAS, BRAF, and MYC, which are associated with elevated reactive oxygen species (ROS) production, also stimulate compensatory antioxidant mechanisms (Son et al