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This may directly affect gene transcription or recruit transcription factors to specific promoter regions

U.KimE.et al (2022)

doi:10.1016/B978-0-12-386933-3.00003-0

Two athletes with identical VOmax values, training volumes, and diets may respond differently to collagen peptide supplementation, because their connective-tissue genetics, inflammatory profiles, and gut-absorption kinetics differ

Promising, but still unproven at the level of evidence you'd want before calling it a first-line treatment

Less frequent sessions may be more effective Finding: Reducing microneedling session frequency (e.g., fortnightly rather than weekly) showed a positive influence on treatment outcomes