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In a gastric tumor model, 1D228 had a striking inhibitory effect on tumor growth

Angle the needle and slowly allow water to slide down and gently contact the lyophilized material

Remove from freezer only what you will use and keep it refrigerated thereafter

The approval was backed by the Phase II open-label AGAVE-201 trial, where treatment with a 0.3-mg/kg dose of Niktimvo elicited an overall response rate of 75%, with a median time to response of 1.5 months