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The investigators reported concentration-dependent reductions in fat mass and adipose-tissue NNMT activity without significant changes in lean mass or food intake

thus, glutamine supplementation is beneficial in patients with critical illness

Conversely, certain GLP-1 receptor agonists, such as exenatide, have shown neuroprotective effects in clinical trials, indicating the potential for cross-therapeutic benefits (Troshneva and Ametov, 2022)