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Key risk groups include: Older Adults: As people age, the stomach produces less acid, which is necessary to absorb Vitamin B12 from food

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Clin Cancer Res 23:42904300 Zhu C, Song Z, Wang A, Srinivasan S, Yang G, Greco R et al (2020) Isatuximab acts through Fc-dependent, independent, and direct pathways to kill multiple myeloma cells

Advanced Considerations in Peptide Reconstitution Impact of Peptide Modifications on Reconstitution Peptides with chemical modifications or complex structures may require specific reconstitution protocols

Avoid repeated freeze-thaw cycles after preparation

The timing of B12 supplementation is generally flexible and should be guided by personal preference and tolerability