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[DOI] [PubMed] [Google Scholar] Lordan R

Long-term l-carnitine supplementation has demonstrated positive support for cardiovascular health after a 3-year follow-up in adult subjects

4 L-Carnitine to Promote Heart Health: Research on the effects of this amino acid for those with heart concerns has focused on taking between one to three grams orally every day for up to 34 months

They find that for the efficacy of l-carnitine on fasting plasma glucose (FPG), 2 g/day l-carnitine is required for at least 36.1 weeks

Cancer 23 , 7894 (2023)

(Waldner 2006) A double-blind RCT (n=30) in patients receiving high-dose interleukin-2 therapy reported a reduction in serious cardiac events (e.g., arrhythmias and acute heart failure) with L-carnitine use compared to no therapy, but the small sample size and heterogeneity of the cancer types limit generalizability