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The GCKR locus, responsible for encoding the glucokinase regulatory protein, might contribute to urate production through glycolysis, while several hyperuricemia-associated loci contain genes which encode transcription factors, growth factors and regulators of purine synthesis

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We note that all individual measures comprising the Safety of Care group are already risk adjusted for clinical factors at the measure level prior to reporting, and thus such differences are already implicitly factored into the Safety of Care measure group score

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Research on diet-induced obese mice indicates that fat cell size decreased by approximately 30% and fat volume decreased by around 40%