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Deficiency of Thiamine can result in nerve disorders

Magerl, M., Paus, R., Farjo, N., Muller-Rover, S., Peters, E

They obstruct the formation of fat cells by decreasing the activity of PPAR and C/EBP/ and preventing fat cell development by preventing SREBP-1c and downstream lipogenic enzymes (FAS, ACC, SCD-1)