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Prx3 has two catalytic cysteines, as do most of the typical members of the peroxiredoxin family, but can also be regulated by oxidation of certain structural Cys residues [56]

Senescent erythrocytes are characterized by loss of surface area and volume [66], increased cell density [67], reduced deformability [68], cation loss [69], membrane desialylation [70], enzymatic dysregulation [69], oxidative stress [71], hemichrome abundance [69], elevated levels of glycated hemoglobin [72], reduced expression of phagocytosis-inhibiting CD47 [73], altered protein 4.1a/protein 4.1b ratio [74], etc

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Unfortunately, we deplete our antioxidant levels in many ways such as ageing, a poor diet and a living a sedentary lifestyle

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The samples were cut into 60 nm thin sections and were observed with a 200 kV transmission electron microscope (Tecnai G2 20 TWIN, 0.24 nm/200 kV, FEI Company, USA)