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Onceweekly tirzepatide versus once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes (SURPASS-3): a randomised, open-label, parallel-group, phase 3 trial

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In contrast, the C-terminal fragment of amylin interacts with the extracellular domains of the calcitonin receptor and RAMP [16]