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Phytomedicine International Journal Phytotherapy Phytopharmacology 135, 156120

Detection in this age group often prompts evaluation for accidental ingestion or exposure

Increasing doses of medication should be tied to improving function in activities of daily living (e.g., work, parenting, sexual intimacy, ability to exercise) rather than to just relief of pain

In limited data it's generally reported as well-tolerated, but human safety data is still limited and long-term effects aren't fully characterized

Lang D, Kredan MB, Moat SJ, Hussain SA, Powell CA, Bellamy MF, Powers HJ, and Lewis MJ (2000)

Humanin was discovered in 2001, while MOTS-c is a more recent discovery