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Danger with hormone-sensitive tumors

Notes 7, 813

Chen et al., 2023)

Aggravated accumulation of S disrupts mitochondrial biogenesis and function by dysregulating the AMPK-CREB-PGC-1 pathway (Shi et al., 2005), which regulates Sirt3 and mitochondrial defence (Park et al., 2020), reported that restoration of Sirt3 expression through the AMPK agonist 5-aminoimidazole-4-carboxamide riboside (AICAR) could recover mitochondrial dynamics and mitophagy

doi: 10.1093/nar/gkaa407 26 FinotelloFMayerCPlattnerCLaschoberGRiederDHacklHet al

Despite a plethora of primary physiological functions, several studies have shown an imbalance between arginase and NOS activity in oxidative stress conditions