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Australia Medical Device Regulations Definition The Therapeutic Goods Administration (TGA) oversees the supply of medical devices and in vitro diagnostic (IVD) devices in Australia

The role of OS in ALS pathology, whether as a primary cause of disease or a secondary consequence, is now well recognized and many preclinical and clinical studies have consistently demonstrated that the disease is characterized by high levels of OS markers able to induce cellular damage, impaired cell signalling, and finally cell death [25, 86]

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However, low solubility and low targeting during drug delivery remain an insurmountable gap in DFO therapy