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Several metabolites mentioned above, such as SBAs, TMAO, and HS, had been implicated in promoting CRC development by inducing chronic inflammation, DNA damage, and activation of oncogenic signaling pathways (Ajouz et al., 2014

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During dialysis, patients experience subnormal plasma/serum free carnitine concentrations [13] with plasma levels dropping by 60% with a slow replacement from carnitine stores such as from skeletal muscle during the interdialytic period

80.9 1.8 kg, p = 0.007) after carnitine supplementation for 4 weeks ( Randomization, blinding, and intervention Following a 2-week run-in period, the participants were randomly allocated to the L-carnitine + synbiotic or L-carnitine + placebo groups via block randomization in a 1:1 ratio, in blocks of two, stratified by age, using the Random Allocation Software (RAS)

Zhang T, Li R, Han X, Chu Y, Wang C, Chi N, et al

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