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However, efforts must also focus on the interim strategy to slow neuron losses in brain structures impacted including neocortices, hippocampus, locus ceruleus and the nucleus basalis of Meynert by stimulating synaptogenesis, neurogenesis and reducing neuroinflammation and oxidative stress

There is abundant evidence that oxidant stress may play an important role in the modification of vascular thromboresistance in moderate hyperhomocysteinemia

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The study protocol was approved by the Institutional Review Board of Bhumibol Adulyadej Hospital and was registered in the Thai Clinical Trials Registry (TCTR)

Mueller LL

However, it is worth noting that the detection of urinary excretion has a strong correlation with the intake dose of flavonoids, so these data may only have some reference value at present, and the specific differences need to be further explored