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It has also been reported that the activation of the Keap1/Nrf2/ARE signalling pathway prevents bone loss in osteoporosis [62, 63]

CpG methylation prevents the binding of several of these factors

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In pyroptosis, mitochondrial outer membrane permeabilization (MOMP) participates in the leakage of cytochrome c from the mitochondrion to the cytosol and subsequently activates caspase proteases and causes cell death [18]

could attenuate gliosis and edema (77, 80)