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Xie Y, Lowry WE., "Manipulation of neural progenitor fate through the oxygen sensing pathway", Methods (2017)

These 3D DRG-like structures were generated by culturing single iPSC aggregates in low-adhesion 96-well plates for 16 days in vitro and exposing them to a sequential combination of small molecules that differentiate iPSCs into neural crest neuronal derivatives [12]